<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE book PUBLIC "-//NLM//DTD BITS Book Interchange DTD v2.3 20210610//EN" "BITS-book2.3.dtd"> <book xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" book-type="conference-proceedings" dtd-version="2.3" xml:lang="ru"> <front> <book-meta>  <book-id book-id-type="isbn">978-5-907561-33-5</book-id>   <book-id pub-id-type="doi">10.31483/a-10364</book-id>   <title-group>  <book-title xml:lang="ru">Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии</book-title>   <trans-title-group xml:lang="en"> <trans-title>Fundamental and applied research for key propriety areas of bioecology and biotechnology</trans-title> </trans-title-group>  </title-group>  <description xml:lang="ru"> <p>В сборнике представлены статьи участников V Всероссийской научно-практической конференции с международным участием «Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии». В материалах сборника приведены результаты теоретических и прикладных изысканий представителей научного и образовательного сообщества в области биологии и медицины.</p> </description>   <contrib-group>  <contrib contrib-type="editor" id="editor1">  <contrib-id contrib-id-type="role">chief_editor</contrib-id>    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> <email xlink:type="simple">antonov_67@mail.ru</email> </contrib>  <contrib contrib-type="editor" id="editor2">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ленгесова</surname> <given-names>Наталья Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Lengesova</surname> <given-names>Natal&#039;ia Anatol&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7512-6386</contrib-id> <email xlink:type="simple">lengesova@yandex.ru</email> </contrib>  </contrib-group>   <contrib-group>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm1">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm2">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm3">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ленгесова</surname> <given-names>Наталья Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Lengesova</surname> <given-names>Natal&#039;ia Anatol&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7512-6386</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm4">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Беззубенкова</surname> <given-names>Ольга Евгеньевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Bezzubenkova</surname> <given-names>Ol&#039;ga Evgen&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3243-6381</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm5">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Коняев</surname> <given-names>Игорь Сергеевич</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Koniaev</surname> <given-names>Igor&#039; Sergeevich</given-names> </name>  </name-alternatives>   </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm6">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Масленников</surname> <given-names>Андрей Викторович</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Maslennikov</surname> <given-names>Andrei Viktorovich</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1421-7484</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm7">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Куницына</surname> <given-names>Анастасия Владимировна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Khambikova</surname> <given-names>Anastasiia Vladimirovna</given-names> </name>  </name-alternatives>   </contrib>  </contrib-group>   <event>  <event-desc xml:lang="ru">Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии</event-desc>   <event-desc xml:lang="en">Fundamental and applied research for key propriety areas of bioecology and biotechnology</event-desc>   <conf-date> <day>20</day> <month>05</month> <year>2022</year> </conf-date>    <conf-loc xml:lang="ru">Ульяновск</conf-loc>  </event>   <publisher> <publisher-name>ИД «Среда»</publisher-name> </publisher>    <pub-date pub-type="collection"> <year>2022</year> </pub-date>    <permissions> <copyright-statement>Copyright &#x00A9; Антонова Е. И., Куницына А. В., Ярушкина Н. Г., Гуськов Г. Ю., Эгова С. А., 2022</copyright-statement> <copyright-year>2022</copyright-year> <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"> <license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p> </license> </permissions>  </book-meta> <book-part book-part-type="conference-paper"> <book-part-meta>  <book-id pub-id-type="doi">10.31483/r-102506</book-id>   <book-id custom-type="publisher-id" pub-id-type="custom">102506</book-id> <title-group>  <chapter-title xml:lang="ru">Формирование и анализ метрик асимметрии и границы образований кожи (невус, меланома) по изображению на основе дерматоскопических признаков</chapter-title>   <trans-title-group xml:lang="en"> <trans-title>Formation and Analysis of Asymmetry Metrics and Boundaries of Skin Formations (Nevus, Melanoma) By Image Based on Dermatoscopic Signs</trans-title> </trans-title-group>  </title-group>  <contrib-group>   <contrib contrib-type="author" id="author1"> <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id>  <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">antonov_67@mail.ru</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author2">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Куницына</surname> <given-names>Анастасия Владимировна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Khambikova</surname> <given-names>Anastasiia Vladimirovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">nastya010994@mail.ru</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author3">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ярушкина</surname> <given-names>Надежда Глебовна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Iarushkina</surname> <given-names>Nadezhda Glebovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">jng@ulstu.ru</email> <xref ref-type="aff" rid="aff2"/> </contrib>   <contrib contrib-type="author" id="author4"> <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3616-4440</contrib-id>  <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Гуськов</surname> <given-names>Глеб Юрьевич</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Guskov</surname> <given-names>Gleb Iurevich</given-names> </name>   </name-alternatives>  <email xlink:type="simple">guskovgleb@gmail.com</email> <xref ref-type="aff" rid="aff2"/> </contrib>   <contrib contrib-type="author" id="author5">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Эгова</surname> <given-names>София Александровна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Egova</surname> <given-names>Sofiia Aleksandovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">sofiakulymanova@gmail.com</email> <xref ref-type="aff" rid="aff2"/> </contrib>   <aff-alternatives id="aff1">   <aff xml:lang="ru">  <institution>Научно-исследовательский центр фундаментальных и прикладных проблем биоэкологии и биотехнологии ФГБОУ ВО «Ульяновский государственный педагогический университет им. И.Н. Ульянова»</institution>   <country>Россия</country> </aff>    <aff xml:lang="en">  <institution>Nauchno-issledovatel&#039;skii tsentr fundamental&#039;nykh i prikladnykh problem bioekologii i biotekhnologii FGBOU VO &quot;Ul&#039;ianovskii gosudarstvennyi pedagogicheskii universitet im. I.N. Ul&#039;ianova&quot;</institution>   <country>Russia</country> </aff>   </aff-alternatives>  <aff-alternatives id="aff2">   <aff xml:lang="ru">  <institution-wrap> <institution-id institution-id-type="ror">00ksn4909</institution-id> <institution>ФГБОУ ВО «Ульяновский государственный технический университет»</institution> </institution-wrap>   <country>Россия</country> </aff>    <aff xml:lang="en">  <institution-wrap> <institution-id institution-id-type="ror">00ksn4909</institution-id> <institution>FSBEI of HE «Ulyanovsk State Technical University»</institution> </institution-wrap>   <country>Russia</country> </aff>   </aff-alternatives>  </contrib-group>   <fpage>128</fpage> <lpage>138</lpage>   <abstract xml:lang="ru"> <p>поддержка принятия клинических решений, анализ изображений на основе искусственного интеллекта является особенно многообещающей областью исследований в области онкологии. Успешное лечение возможно только в случае обнаружения меланомы на ранних стадиях ее биологического развития и сопровождается хорошим долгосрочным прогнозом, не снижая качества жизни больных. В статье предлагаются оригинальные метрики по расчету показателей асимметрии и границы образования кожи по его изображению. Данные метрики подразумевают настройку пороговых значений, выставляемых экспертами, что поможет компенсировать разницу в качестве изображения, особенностей производства фотографии и т. д. По метрикам строятся временные ряды, которые можно прогнозировать при помощи классических и интеллектуальных моделей прогнозирования.</p> </abstract>           <kwd-group xml:lang="ru">  <kwd>меланома</kwd>  <kwd>невус</kwd>  <kwd>ABCDE-анализ</kwd>  <kwd>система поддержки принятия решения</kwd>  <kwd>временной ряд</kwd>  <kwd>прогнозирование временных рядов</kwd>  </kwd-group>        <funding-group>  <funding-statement>Исследование выполнено при финансовой поддержке РФФИ и Ульяновской области в рамках научного проекта №19-47-730006</funding-statement>   <award-group>  <award-id award-id-type="crossref-funder-id">501100002261</award-id>   <award-id>19-47-730006</award-id>    <funding-source>Russian Foundation for Basic Research</funding-source>  </award-group>  </funding-group>  </book-part-meta> </book-part> </front>  <back> <ref-list> <title>References</title>  <ref id="ref1"> <label>1</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Британский журнал дерматологии [Электронный ресурс] – Режим доступа: https://www.maxmedical.ru/scientific/DANAOS_RU_EN.pdf (дата обращения: 17.05.2022).</mixed-citation>    </citation-alternatives> <element-citation publication-type="web">   <article-title>Британский журнал дерматологии</article-title>         <ext-link ext-link-type="uri">https://www.maxmedical.ru/scientific/DANAOS_RU_EN.pdf</ext-link>      </element-citation> </ref>  <ref id="ref2"> <label>2</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Гаврилов Д.А. Автоматизированная диагностика меланомы кожи на основе математической модели искусственной сверточной нейронной сети / Д.А.  Гаврилов [Электронный ресурс]. – Режим доступа: https://www.rpmj.ru/rpmj/article/view/299/260 (дата обращения: 17.05.2022).</mixed-citation>    </citation-alternatives> <element-citation publication-type="web">  <person-group person-group-type="author">  <name> <surname>Гаврилов</surname> <given-names>Д. А.</given-names> </name>  </person-group>   <article-title>Автоматизированная диагностика меланомы кожи на основе математической модели искусственной сверточной нейронной сети</article-title>         <ext-link ext-link-type="uri">https://www.rpmj.ru/rpmj/article/view/299/260</ext-link>      </element-citation> </ref>  <ref id="ref3"> <label>3</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Давыдов М.И. Меланоцитарные невусы / М.И. Давыдов,  В.И. Чиссов,  В.А.  Молочков // Практическая медицина. – 2011. – Т. 5, №37. – С. 36–40.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Давыдов</surname> <given-names>М. И.</given-names> </name>  <name> <surname>Чиссов</surname> <given-names>В. А.</given-names> </name>  </person-group>   <article-title>Меланоцитарные невусы</article-title> <source>Практическая медицина</source> <year>2011</year>  <issue>Т. 5, №37</issue> <fpage>36</fpage> <lpage>40</lpage>         </element-citation> </ref>  <ref id="ref4"> <label>4</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Имянитов Е.Н. Эпидемиология и биология опухолей кожи / Е.Н. Имянитов // Практическая онкология. – 2012. – №. 2. – С. 61.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Имянитов</surname> <given-names>Е. Н.</given-names> </name>  </person-group>   <article-title>Эпидемиология и биология опухолей кожи</article-title> <source>Практическая онкология</source> <year>2012</year>  <issue>№. 2</issue>           </element-citation> </ref>  <ref id="ref5"> <label>5</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Мамунов М.В. Диагностическая эффективность основных дерматоскопических симптомов и алгоритмов для выявления меланомы кожи / М.В. Мамунов, А.В. Патрушев // Клиническая медицина. – 2021. – Том 40, №1. – С. 45–52.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Мамунов</surname> <given-names>М. В.</given-names> </name>  <name> <surname>Патрушев</surname> <given-names>А. В.</given-names> </name>  </person-group>   <article-title>Диагностическая эффективность основных дерматоскопических симптомов и алгоритмов для выявления меланомы кожи</article-title> <source>Клиническая медицина</source> <year>2021</year>  <issue>Том 40, №1</issue> <fpage>45</fpage> <lpage>52</lpage>         </element-citation> </ref>  <ref id="ref6"> <label>6</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Новик А.В. Меланома кожи: новые подходы / А.В. Новик // Практическая онкология. – 2011. – №. 1. – С. 12.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Новик</surname> <given-names>А. В.</given-names> </name>  </person-group>   <article-title>Меланома кожи: новые подходы</article-title> <source>Практическая онкология</source> <year>2011</year>  <issue>№. 1</issue>           </element-citation> </ref>  <ref id="ref7"> <label>7</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Приказ Минздравсоцразвития РФ от 16.03.2010 №151н «Об утверждении Порядка оказания медицинской помощи больным дерматовенерологического профиля и больным лепрой».</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">   <article-title>Приказ Минздравсоцразвития РФ от 16.03.2010 №151н «Об утверждении Порядка оказания медицинской помощи больным дерматовенерологического профиля и больным лепрой»</article-title>               </element-citation> </ref>  <ref id="ref8"> <label>8</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Саламова И.В. Проблема профилактики меланомы кожи у пациентов с множественными невусами / И.В. Саламова, В.В. Мордовцева, И.А. Ламоткин // Клиническая дерматология и венерология. – 2014. – №2. – С. 110–14.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Саламова</surname> <given-names>И. В.</given-names> </name>  <name> <surname>Мордовцева</surname> <given-names>В. В.</given-names> </name>  <name> <surname>Ламоткин</surname> <given-names>И. А.</given-names> </name>  </person-group>   <article-title>Проблема профилактики меланомы кожи у пациентов с множественными невусами</article-title> <source>Клиническая дерматология и венерология</source> <year>2014</year>  <issue>№2</issue> <fpage>110</fpage> <lpage>14</lpage>         </element-citation> </ref>  <ref id="ref9"> <label>9</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Сойер Г.П. Дерматоскопия / Г.П. Сойер, Д. Аргенциано, Р. Гофман-Велленгоф, А. Залаудек; пер. с англ. – М.: МЕДпресс-информ, 2014. – 240 с. : ил.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Сойер</surname> <given-names>Г. П.</given-names> </name>  <name> <surname>Аргенциано</surname> <given-names>Д.</given-names> </name>  <name> <surname>Гофман-Велленгоф</surname> <given-names>Р.</given-names> </name>  </person-group>   <article-title>Дерматоскопия</article-title>               <publisher-loc>Залаудек;</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref10"> <label>10</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Соколов Д.В. Дерматоскопия в ранней диагностике и скрининге меланомы кожи: автореф. дис. … д-ра мед. наук / Д.В. Соколов. – М., 2009. – 25 с.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Соколов</surname> <given-names>Д. В.</given-names> </name>  </person-group>   <article-title>Дерматоскопия в ранней диагностике и скрининге меланомы кожи</article-title>               <publisher-loc>М.</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref11"> <label>11</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Bastian B.C. The molecular pathology of melanoma: An integrated taxonomy of melanocytic neoplasia // Annu Rev Pathol. 9:239–271. 2014.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Bastian</surname> <given-names>B. C.</given-names> </name>  </person-group>   <article-title>The molecular pathology of melanoma: An integrated taxonomy of melanocytic neoplasia</article-title> <source>Annu Rev Pathol. 9:239–271. 2014</source>              </element-citation> </ref>  <ref id="ref12"> <label>12</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Bertolotto C. Melanoma: from melanocyte to genetic alterations and clinical options // Scientifica. – 2013. – P. 22.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Bertolotto</surname> <given-names>C.</given-names> </name>  </person-group>   <article-title>Melanoma: from melanocyte to genetic alterations and clinical options</article-title> <source>Scientifica</source> <year>2013</year>  <issue>P. 22</issue>           </element-citation> </ref>  <ref id="ref13"> <label>13</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Bevona C., Goggins W., Quinn T., Fullerton J., Tsao H. Cutaneous melanomas associated with nevi // Arch. Dermatol. 139, 1620–1624; discussion 1624 (2003).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Bevona</surname> <given-names>C.</given-names> </name>  <name> <surname>Goggins</surname> <given-names>W.</given-names> </name>  <name> <surname>Quinn</surname> <given-names>T.</given-names> </name>  <name> <surname>Fullerton</surname> <given-names>J.</given-names> </name>  <name> <surname>Tsao</surname> <given-names>H.</given-names> </name>  </person-group>   <article-title>,, Cutaneous melanomas associated with nevi</article-title> <source>Arch. Dermatol. 139, 1620–1624; discussion 1624 (2003)</source>              </element-citation> </ref>  <ref id="ref14"> <label>14</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Bradford P.T., Freedman D.M., Goldstein A.M., Tucker M.A. Increased risk of second primary cancers after a diagnosis of melanoma // Arch. Dermatol. 2010;146 (3):265–72.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Bradford</surname> <given-names>P. T.</given-names> </name>  <name> <surname>Freedman</surname> <given-names>D. M.</given-names> </name>  <name> <surname>Goldstein</surname> <given-names>A. M.</given-names> </name>  <name> <surname>Tucker</surname> <given-names>M. A.</given-names> </name>  </person-group>   <article-title>, Increased risk of second primary cancers after a diagnosis of melanoma</article-title> <source>Arch. Dermatol. 2010;146 (3):265–72</source>              </element-citation> </ref>  <ref id="ref15"> <label>15</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Caini S., Boniol M., Botteri E., Tosti G., Bazolli B., Russell-Edu W., Giusti F., Testori A., Gandini S. The risk of developing a second primary cancer in melanoma patients: a comprehensive review of the literature and meta-analysis // J. Dermatol. Science. 2014;75(1):3–9.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Caini</surname> <given-names>S.</given-names> </name>  <name> <surname>Boniol</surname> <given-names>M.</given-names> </name>  <name> <surname>Botteri</surname> <given-names>E.</given-names> </name>  <name> <surname>Tosti</surname> <given-names>G.</given-names> </name>  <name> <surname>Bazolli</surname> <given-names>B.</given-names> </name>  <name> <surname>Russell-Edu</surname> <given-names>W.</given-names> </name>  <name> <surname>Giusti</surname> <given-names>F.</given-names> </name>  <name> <surname>Testori</surname> <given-names>A.</given-names> </name>  <name> <surname>Gandini</surname> <given-names>S.</given-names> </name>  </person-group>   <article-title>,,,,,, The risk of developing a second primary cancer in melanoma patients: a comprehensive review of the literature and meta-analysis</article-title> <source>J. Dermatol. Science. 2014;75(1):3–9</source>              </element-citation> </ref>  <ref id="ref16"> <label>16</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Clark W.H. et al. A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma // Human Pathology. – 1984. – Vol. 15, №12. – P. 1147–1165.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Clark</surname> <given-names>W. H.</given-names> </name>  </person-group>   <article-title>et al. A study of tumor progression: the precursor lesions of superficial spreading and nodular melanoma</article-title> <source>Human Pathology</source> <year>1984</year>  <issue>Vol. 15, №12</issue>           </element-citation> </ref>  <ref id="ref17"> <label>17</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Fernandes N.C. The risk of cutaneous melanoma in melanocytic nevi // An. Bras. Dermatol 2013;88(2):314–15.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Fernandes</surname> <given-names>N. C.</given-names> </name>  </person-group>   <article-title>The risk of cutaneous melanoma in melanocytic nevi</article-title> <source>An. Bras.88(2):314–15</source>              <publisher-loc>Dermatol 2013;</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref18"> <label>18</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Fried L., Tan A., Bajaj S., Liebman T.N., Polsky D., Stein J.A. Technological advances for the detection of melanoma: Part I. Advances in diagnostic techniques // J Am Acad Dermatol. (2020) 83:983–92.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Fried</surname> <given-names>L.</given-names> </name>  <name> <surname>Tan</surname> <given-names>A.</given-names> </name>  <name> <surname>Bajaj</surname> <given-names>S.</given-names> </name>  <name> <surname>Liebman</surname> <given-names>T. N.</given-names> </name>  <name> <surname>Polsky</surname> <given-names>D.</given-names> </name>  <name> <surname>Stein</surname> <given-names>J. A.</given-names> </name>  <name> <surname>Part</surname> <given-names>I.</given-names> </name>  </person-group>   <article-title>,,, Technological advances for the detection of melanoma: Advances in diagnostic techniques</article-title> <source>J Am Acad Dermatol. (2020) 83:983–92</source>              </element-citation> </ref>  <ref id="ref19"> <label>19</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Glasziou P.P., Jones M.A., Pathirana T., Barratt A.L., Bell K.J. Estimating the magnitude of cancer overdiagnosis in Australia // Med J Austral. (2020) 212:163–8.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Glasziou</surname> <given-names>P. P.</given-names> </name>  <name> <surname>Jones</surname> <given-names>M. A.</given-names> </name>  <name> <surname>Pathirana</surname> <given-names>T.</given-names> </name>  <name> <surname>Barratt</surname> <given-names>A. L.</given-names> </name>  <name> <surname>Bell</surname> <given-names>K. J.</given-names> </name>  </person-group>   <article-title>,, Estimating the magnitude of cancer overdiagnosis in Australia</article-title> <source>Med J Austral. (2020) 212:163–8</source>              </element-citation> </ref>  <ref id="ref20"> <label>20</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Haenssle H.A., Mograby N., Ngassa A., Buhl T., Emmert S., Schön M.P., Rosenberger A., Bertsch H.P. Association of patient risk factors and frequency of nevus-associated cutaneous melanomas // JAMA. Dermatol. 2016; 152(3):291–98.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Haenssle</surname> <given-names>H. A.</given-names> </name>  <name> <surname>Mograby</surname> <given-names>N.</given-names> </name>  <name> <surname>Ngassa</surname> <given-names>A.</given-names> </name>  <name> <surname>Buhl</surname> <given-names>T.</given-names> </name>  <name> <surname>Emmert</surname> <given-names>S.</given-names> </name>  <name> <surname>Schön</surname> <given-names>M. P.</given-names> </name>  <name> <surname>Rosenberger</surname> <given-names>A.</given-names> </name>  <name> <surname>Bertsch</surname> <given-names>H. P.</given-names> </name>  </person-group>   <article-title>,,,,, Association of patient risk factors and frequency of nevus-associated cutaneous melanomas</article-title> <source>JAMA. Dermatol. 2016; 152(3):291–98</source>              </element-citation> </ref>  <ref id="ref21"> <label>21</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Janda M., Horsham C., Koh U., Gillespie N., Loescher L.J., Vagenas D., et al. Redesigning skin cancer early detection and care using a new mobile health application: protocol of the SKIN research project, a randomised controlled trial // Dermatology. (2019) 235:11–8.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Janda</surname> <given-names>M.</given-names> </name>  <name> <surname>Horsham</surname> <given-names>C.</given-names> </name>  <name> <surname>Koh</surname> <given-names>U.</given-names> </name>  <name> <surname>Gillespie</surname> <given-names>N.</given-names> </name>  <name> <surname>Loescher</surname> <given-names>L. J.</given-names> </name>  <name> <surname>Vagenas</surname> <given-names>D.</given-names> </name>  </person-group>   <article-title>,,,, et al. Redesigning skin cancer early detection and care using a new mobile health application: protocol of the SKIN research project, a randomised controlled trial</article-title> <source>Dermatology. (2019) 235:11–8</source>              </element-citation> </ref>  <ref id="ref22"> <label>22</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Kim J.K., Nelson K.C. Dermoscopic features of common nevi: a review // Dermoscopy 2012;147(2):141–8).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Kim</surname> <given-names>J. K.</given-names> </name>  <name> <surname>Nelson</surname> <given-names>K. C.</given-names> </name>  </person-group>   <article-title>Dermoscopic features of common nevi: a review</article-title> <source>147(2):141–8)</source>              <publisher-loc>Dermoscopy 2012;</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref23"> <label>23</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Koh U., Horsham C., Soyer H.P., Loescher L.J., Gillespie N., Vagenas D., et al. Consumer acceptance and expectations of a mobile health application to photograph skin lesions for early detection of melanoma // Dermatology. (2019) 235:4–10.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Koh</surname> <given-names>U.</given-names> </name>  <name> <surname>Horsham</surname> <given-names>C.</given-names> </name>  <name> <surname>Soyer</surname> <given-names>H. P.</given-names> </name>  <name> <surname>Loescher</surname> <given-names>L. J.</given-names> </name>  <name> <surname>Gillespie</surname> <given-names>N.</given-names> </name>  <name> <surname>Vagenas</surname> <given-names>D.</given-names> </name>  </person-group>   <article-title>,,,, et al. Consumer acceptance and expectations of a mobile health application to photograph skin lesions for early detection of melanoma</article-title> <source>Dermatology. (2019) 235:4–10</source>              </element-citation> </ref>  <ref id="ref24"> <label>24</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Kolm I., French L., Braun R.P. Dermoscopy in the xxi century: past, present and future // Giornale Italiano di Dermatologia e Venereologia 2010;145(1):99–110.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Kolm</surname> <given-names>I.</given-names> </name>  <name> <surname>French</surname> <given-names>L.</given-names> </name>  <name> <surname>Braun</surname> <given-names>R. P.</given-names> </name>  </person-group>   <article-title>Dermoscopy in the xxi century: past, present and future</article-title> <source>Giornale Italiano di Dermatologia e145(1):99–110</source>              <publisher-loc>Venereologia 2010;</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref25"> <label>25</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Kong F., Horsham C., Rayner J., Simunovic M., O&#039;Hara M., Soyer H.P., et al. Consumer preferences for skin cancer screening using mobile teledermoscopy: a qualitative study // Dermatology. (2020) 236:97–104.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Kong</surname> <given-names>F.</given-names> </name>  <name> <surname>Horsham</surname> <given-names>C.</given-names> </name>  <name> <surname>Rayner</surname> <given-names>J.</given-names> </name>  <name> <surname>Simunovic</surname> <given-names>M.</given-names> </name>  <name> <surname>O&#039;Hara</surname> <given-names>M.</given-names> </name>  <name> <surname>Soyer</surname> <given-names>H. P.</given-names> </name>  </person-group>   <article-title>,,,, et al. Consumer preferences for skin cancer screening using mobile teledermoscopy: a qualitative study</article-title> <source>Dermatology. (2020) 236:97–104</source>              </element-citation> </ref>  <ref id="ref26"> <label>26</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Lee K.J., di Meo N., Yelamos O., Malvehy J., Zalaudek I., Soyer H.P. Dermoscopy confocal microscopy // Cutaneous Melanoma. 6th ed. Cham: Springer (2019) 1–50.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Lee</surname> <given-names>K. J.</given-names> </name>  <name> <surname>Meo</surname> <given-names>N.</given-names> </name>  <name> <surname>Yelamos</surname> <given-names>O.</given-names> </name>  <name> <surname>Malvehy</surname> <given-names>J.</given-names> </name>  <name> <surname>Zalaudek</surname> <given-names>I.</given-names> </name>  <name> <surname>Soyer</surname> <given-names>H. P.</given-names> </name>  </person-group>   <article-title>di,,,, Dermoscopy confocal microscopy</article-title> <source>Cutaneous Melanoma. 6th ed. Cham: Springer (2019) 1–50</source>              </element-citation> </ref>  <ref id="ref27"> <label>27</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Long G.V. et al. Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma // J. Clin. Oncol. 29, 1239–1246 (2011).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Long</surname> <given-names>G. V.</given-names> </name>  </person-group>   <article-title>et al. Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma</article-title> <source>J. Clin. Oncol. 29, 1239–1246 (2011)</source>              </element-citation> </ref>  <ref id="ref28"> <label>28</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Mort R.L., Jackson I.J., Patton E.E. The melanocyte lineage in development and disease // Development 142, 620–632 (2015).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Mort</surname> <given-names>R. L.</given-names> </name>  <name> <surname>Jackson</surname> <given-names>I. J.</given-names> </name>  <name> <surname>Patton</surname> <given-names>E. E.</given-names> </name>  </person-group>   <article-title>The melanocyte lineage in development and disease</article-title> <source>632 (2015)</source>              <publisher-loc>Development 142, 620–</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref29"> <label>29</label> <citation-alternatives>  <mixed-citation xml:lang="ru">OpenCV-Python Tutorials [Электронный ресурс] – Режим доступа: https://docs.opencv.org/4.x/d6/d00/tutorial_py_root.html (дата обращения: 05.03.2022).</mixed-citation>    </citation-alternatives> <element-citation publication-type="web">   <article-title>OpenCV-Python Tutorials</article-title>         <ext-link ext-link-type="uri">https://docs.opencv.org/4.x/d6/d00/tutorial_py_root.html</ext-link>      </element-citation> </ref>  <ref id="ref30"> <label>30</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Patel S., Kim D., Lacey C. GNA-11 mutation in a patient with cutaneous origin melanoma: a case report // Journal of Medicine. – 2016. – №95. – Р. 23–27.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Patel</surname> <given-names>S.</given-names> </name>  <name> <surname>Kim</surname> <given-names>D.</given-names> </name>  <name> <surname>Lacey</surname> <given-names>C.</given-names> </name>  </person-group>   <article-title>GNA-11 mutation in a patient with cutaneous origin melanoma: a case report</article-title> <source>Journal of Medicine</source> <year>2016</year>  <issue>№95</issue>           </element-citation> </ref>  <ref id="ref31"> <label>31</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Puri P., Comfere N., Drage L.A., Shamim H., Bezalel S.A., Pittelkow M.R., et al. Deep learning for dermatologists: Part II. Current applications // J Am Acad Dermatol. (2020).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Puri</surname> <given-names>P.</given-names> </name>  <name> <surname>Comfere</surname> <given-names>N.</given-names> </name>  <name> <surname>Drage</surname> <given-names>L. A.</given-names> </name>  <name> <surname>Shamim</surname> <given-names>H.</given-names> </name>  <name> <surname>Bezalel</surname> <given-names>S. A.</given-names> </name>  <name> <surname>Pittelkow</surname> <given-names>M. R.</given-names> </name>  </person-group>   <article-title>,,,, et al. Deep learning for dermatologists: Part II. Current applications</article-title> <source>J Am Acad Dermatol. (2020)</source>              </element-citation> </ref>  <ref id="ref32"> <label>32</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Roesch A., Burgdorf W., Stolz W., Landthaler M. Dermatoscopy of «dysplastic nevi»: A beacon in diagnostic darkness // European journal of dermatology: EJD 16(5):479–93).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Roesch</surname> <given-names>A.</given-names> </name>  <name> <surname>Burgdorf</surname> <given-names>W.</given-names> </name>  <name> <surname>Stolz</surname> <given-names>W.</given-names> </name>  <name> <surname>Landthaler</surname> <given-names>M.</given-names> </name>  </person-group>   <article-title>, Dermatoscopy of «dysplastic nevi»: A beacon in diagnostic darkness</article-title> <source>European journal of dermatology: EJD 16(5):479–93)</source>              </element-citation> </ref>  <ref id="ref33"> <label>33</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Rose S.E., Argenziano G., Marghoob A.A. Melanomas difficult to diagnose via dermoscopy Dermoscopy in the xxi century: past, present and future // Giornale Italiano di Dermatologia e Venereologia 2010, 145(1):111–26.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Rose</surname> <given-names>S. E.</given-names> </name>  <name> <surname>Argenziano</surname> <given-names>G.</given-names> </name>  <name> <surname>Marghoob</surname> <given-names>A. A.</given-names> </name>  </person-group>   <article-title>Melanomas difficult to diagnose via dermoscopy Dermoscopy in the xxi century: past, present and future</article-title> <source>Giornale Italiano di Dermatologia e1):111–26</source>              <publisher-loc>Venereologia 2010, 145(</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref34"> <label>34</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Rotemberg V., Kurtansky N., Betz-Stablein B., Caffery L., Chousakos E., Codella N., et al. A patient-centric dataset of images and metadata for identifying melanomas using clinical context // Sci Data. 2021; 8: 34.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Rotemberg</surname> <given-names>V.</given-names> </name>  <name> <surname>Kurtansky</surname> <given-names>N.</given-names> </name>  <name> <surname>Betz-Stablein</surname> <given-names>B.</given-names> </name>  <name> <surname>Caffery</surname> <given-names>L.</given-names> </name>  <name> <surname>Chousakos</surname> <given-names>E.</given-names> </name>  <name> <surname>Codella</surname> <given-names>N.</given-names> </name>  </person-group>   <article-title>,,,, et al. A patient-centric dataset of images and metadata for identifying melanomas using clinical context</article-title> <source>Sci Data. 2021; 8: 34</source>              </element-citation> </ref>  <ref id="ref35"> <label>35</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Shain A.H., Bastian B.C. From melanocytes to melanomas // Сancer origins, volume 16, 2016, 345–358.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Shain</surname> <given-names>A. H.</given-names> </name>  <name> <surname>Bastian</surname> <given-names>B. C.</given-names> </name>  </person-group>   <article-title>From melanocytes to melanomas</article-title> <source>Сancer origins, volume 16, 2016, 345–358</source>              </element-citation> </ref>  <ref id="ref36"> <label>36</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Shellenberger R., Nabhan M., Kakaraparthi S. Melanoma screening: a plan for improving early detection // Ann. Med. 2016; 48(3):142–48.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Shellenberger</surname> <given-names>R.</given-names> </name>  <name> <surname>Nabhan</surname> <given-names>M.</given-names> </name>  <name> <surname>Kakaraparthi</surname> <given-names>S.</given-names> </name>  </person-group>   <article-title>Melanoma screening: a plan for improving early detection</article-title> <source>Ann. Med. 2016; 48(3):142–48</source>              </element-citation> </ref>  <ref id="ref37"> <label>37</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Shitara D. et al. Nevus-associated melanomas: clinicopathologic features // Am. J. Clin. Pathol. 142, 485–491 (2014).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Shitara</surname> <given-names>D.</given-names> </name>  </person-group>   <article-title>et al. Nevus-associated melanomas: clinicopathologic features</article-title> <source>Am. J. Clin. Pathol. 142, 485–491 (2014)</source>              </element-citation> </ref>  <ref id="ref38"> <label>38</label> <citation-alternatives>  <mixed-citation xml:lang="ru">SIIM-ISIC Melanoma Classification [Электронный ресурс] – Режим доступа: https://www.kaggle.com/c/siim-isic-melanoma-classification (дата обращения: 05.03.2022).</mixed-citation>    </citation-alternatives> <element-citation publication-type="web">   <article-title>SIIM-ISIC Melanoma Classification</article-title>         <ext-link ext-link-type="uri">https://www.kaggle.com/c/siim-isic-melanoma-classification</ext-link>      </element-citation> </ref>  <ref id="ref39"> <label>39</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Srivastava S., Ghosh S., Kagan J., Mazurchuk R. The PreCancer Atlas (PCA) // Trends Cancer. – 2018. – 4:513–4.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Srivastava</surname> <given-names>S.</given-names> </name>  <name> <surname>Ghosh</surname> <given-names>S.</given-names> </name>  <name> <surname>Kagan</surname> <given-names>J.</given-names> </name>  <name> <surname>Mazurchuk</surname> <given-names>R.</given-names> </name>  </person-group>   <article-title>, The PreCancer Atlas (PCA)</article-title> <source>Trends Cancer</source> <year>2018</year>  <issue>4:513</issue>           </element-citation> </ref>  <ref id="ref40"> <label>40</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Stanganelli I., Dirk M., Elston MD. Dermoscopy // Clinical Procedures, 2018.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Stanganelli</surname> <given-names>I.</given-names> </name>  <name> <surname>Dirk</surname> <given-names>M.</given-names> </name>  </person-group>   <article-title>Elston MD. Dermoscopy</article-title> <source>Clinical</source>              <publisher-loc>Procedures</publisher-loc> <publisher-name></publisher-name>  </element-citation> </ref>  <ref id="ref41"> <label>41</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Tschandl P., Rinner C., Apalla Z., Argenziano G., Codella N., Halpern A., et al. Human-computer collaboration for skin cancer recognition // Nat Med. (2020) 26:1229–34.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Tschandl</surname> <given-names>P.</given-names> </name>  <name> <surname>Rinner</surname> <given-names>C.</given-names> </name>  <name> <surname>Apalla</surname> <given-names>Z.</given-names> </name>  <name> <surname>Argenziano</surname> <given-names>G.</given-names> </name>  <name> <surname>Codella</surname> <given-names>N.</given-names> </name>  <name> <surname>Halpern</surname> <given-names>A.</given-names> </name>  </person-group>   <article-title>,,,, et al. Human-computer collaboration for skin cancer recognition</article-title> <source>Nat Med. (2020) 26:1229–34</source>              </element-citation> </ref>  <ref id="ref42"> <label>42</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Xavier M.H., Drummond-Lage A.P., Baeta C., Rocha L., Almeida A.M., Wainstein A.J. Delay in cutaneous melanoma diagnosis: sequence analyses from suspicion to diagnosis in 211 patients // Medicine. 2016; 95(31):e4396.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Xavier</surname> <given-names>M. H.</given-names> </name>  <name> <surname>Drummond-Lage</surname> <given-names>A. P.</given-names> </name>  <name> <surname>Baeta</surname> <given-names>C.</given-names> </name>  <name> <surname>Rocha</surname> <given-names>L.</given-names> </name>  <name> <surname>Almeida</surname> <given-names>A. M.</given-names> </name>  <name> <surname>Wainstein</surname> <given-names>A. J.</given-names> </name>  </person-group>   <article-title>,,, Delay in cutaneous melanoma diagnosis: sequence analyses from suspicion to diagnosis in 211 patients</article-title> <source>Medicine. 2016; 95(31):e4396</source>              </element-citation> </ref>  <ref id="ref43"> <label>43</label> <citation-alternatives>  <mixed-citation xml:lang="ru">[Электронный ресурс] – Режим доступа: https://www.kaggle.com/code/nxrprime/siim-d3-eda-augmentations-and-resnext/data (дата обращения: 17.05.2022).</mixed-citation>    </citation-alternatives> <element-citation publication-type="web">            <ext-link ext-link-type="uri">https://www.kaggle.com/code/nxrprime/siim-d3-eda-augmentations-and-resnext/data</ext-link>      </element-citation> </ref>  </ref-list> </back>  </book>