<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE book PUBLIC "-//NLM//DTD BITS Book Interchange DTD v2.3 20210610//EN" "BITS-book2.3.dtd"> <book xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" book-type="conference-proceedings" dtd-version="2.3" xml:lang="ru"> <front> <book-meta>  <book-id book-id-type="isbn">978-5-907830-38-7</book-id>   <book-id pub-id-type="doi">10.31483/a-10590</book-id>   <title-group>  <book-title xml:lang="ru">Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии</book-title>   <trans-title-group xml:lang="en"> <trans-title>Fundamental and applied research for key propriety areas of bioecology and biotechnology</trans-title> </trans-title-group>  </title-group>  <description xml:lang="ru"> <p>В сборнике представлены статьи участников VII Всероссийской научно-практической конференции «Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии». В материалах сборника приведены результаты теоретических и прикладных изысканий представителей научного и образовательного сообщества в области биологии и медицины.</p> </description>   <contrib-group>  <contrib contrib-type="editor" id="editor1">  <contrib-id contrib-id-type="role">chief_editor</contrib-id>    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> <email xlink:type="simple">antonov_67@mail.ru</email> </contrib>  <contrib contrib-type="editor" id="editor2">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ленгесова</surname> <given-names>Наталья Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Lengesova</surname> <given-names>Natal&#039;ia Anatol&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7512-6386</contrib-id> <email xlink:type="simple">lengesova@yandex.ru</email> </contrib>  </contrib-group>   <contrib-group>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm1">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm2">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm3">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ленгесова</surname> <given-names>Наталья Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Lengesova</surname> <given-names>Natal&#039;ia Anatol&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7512-6386</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm4">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Беззубенкова</surname> <given-names>Ольга Евгеньевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Bezzubenkova</surname> <given-names>Ol&#039;ga Evgen&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3243-6381</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm5">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Коняев</surname> <given-names>Игорь Сергеевич</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Koniaev</surname> <given-names>Igor&#039; Sergeevich</given-names> </name>  </name-alternatives>   </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm6">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Масленников</surname> <given-names>Андрей Викторович</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Maslennikov</surname> <given-names>Andrei Viktorovich</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1421-7484</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm7">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Куницына</surname> <given-names>Анастасия Владимировна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Khambikova</surname> <given-names>Anastasiia Vladimirovna</given-names> </name>  </name-alternatives>   </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm8">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Фирсова</surname> <given-names>Наталья Викторовна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Firsova</surname> <given-names>Natalia Viktorovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9907-8857</contrib-id> </contrib>  </contrib-group>   <event>  <event-desc xml:lang="ru">Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии</event-desc>   <event-desc xml:lang="en">Fundamental and applied research for key propriety areas of bioecology and biotechnology</event-desc>   <conf-date> <day>28</day> <month>05</month> <year>2024</year> </conf-date>    <conf-loc xml:lang="ru">Ульяновск</conf-loc>  </event>   <publisher> <publisher-name>ИД «Среда»</publisher-name> </publisher>    <pub-date pub-type="collection"> <year>2024</year> </pub-date>    <permissions> <copyright-statement>Copyright &#x00A9; Антонова Е. И., Ачилов А. Б., Фирсова Н. В., Викторов Д. А., 2024</copyright-statement> <copyright-year>2024</copyright-year> <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"> <license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p> </license> </permissions>  </book-meta> <book-part book-part-type="conference-paper"> <book-part-meta>  <book-id pub-id-type="doi">10.31483/r-112104</book-id>   <book-id custom-type="publisher-id" pub-id-type="custom">112104</book-id> <title-group>  <chapter-title xml:lang="ru">Мультиплексная технология xMAP</chapter-title>   <trans-title-group xml:lang="en"> <trans-title>Mul&#039;tipleksnaia tekhnologiia xMAP</trans-title> </trans-title-group>  </title-group>  <contrib-group>   <contrib contrib-type="author" id="author1"> <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id>  <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">antonov_67@mail.ru</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author2">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ачилов</surname> <given-names>Атабег Батырович</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Achilov</surname> <given-names>Atabeg Batyrovich</given-names> </name>   </name-alternatives>  <email xlink:type="simple">a.achilow@inbox.ru</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author3"> <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9907-8857</contrib-id>  <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Фирсова</surname> <given-names>Наталья Викторовна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Firsova</surname> <given-names>Natalia Viktorovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">n-firsova@mail.ru</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author4">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Викторов</surname> <given-names>Денис Александрович</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Viktorov</surname> <given-names>Denis Aleksandrovich</given-names> </name>   </name-alternatives>  <email xlink:type="simple">victorov.da@gmail.com</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <aff-alternatives id="aff1">   <aff xml:lang="ru">  <institution>Научно-исследовательский центр фундаментальных и прикладных проблем биоэкологии и биотехнологии ФГБОУ ВО «Ульяновский государственный педагогический университет им. И.Н. Ульянова»</institution>   <country>Россия</country> </aff>    <aff xml:lang="en">  <institution>Nauchno-issledovatel&#039;skii tsentr fundamental&#039;nykh i prikladnykh problem bioekologii i biotekhnologii FGBOU VO &quot;Ul&#039;ianovskii gosudarstvennyi pedagogicheskii universitet im. I.N. Ul&#039;ianova&quot;</institution>   <country>Russia</country> </aff>   </aff-alternatives>  </contrib-group>   <fpage>56</fpage> <lpage>61</lpage>   <abstract xml:lang="ru"> <p>в статье рассматриваются методы технологии xMAP, сфера применения в области клинических и фундаментальных исследований.</p> </abstract>           <kwd-group xml:lang="ru">  <kwd>технология xMAP</kwd>  <kwd>диагностика мутаций</kwd>  <kwd>методы технологии xMAP</kwd>  <kwd>генотипирование</kwd>  </kwd-group>        <funding-group>  <funding-statement>Статья написана и доклад выполнен в рамках Дополнительного соглашения №073-03-2024-060/1 от 13.02.2024 к Соглашению о предоставлении субсидии из федерального бюджета на финансовое обеспечение выполнения государственного задания на оказание государственных услуг (выполнения работ) №073-03-2024-060 от 18.01.2024, заключенным между ФГБОУ ВО «УлГПУ им. И.Н. Ульянова» и Министерством просвещения Российской Федерации.</funding-statement>   </funding-group>  </book-part-meta> </book-part> </front>  <back> <ref-list> <title>References</title>  <ref id="ref1"> <label>1</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Armstrong B., Stewart M., Mazumder A. Suspension arrays for high throughput, multiplexed single nucleotide polymorphism genotyping // Cytometry, 2000; 40: 102–108.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Armstrong</surname> <given-names>B.</given-names> </name>  <name> <surname>Stewart</surname> <given-names>M.</given-names> </name>  <name> <surname>Mazumder</surname> <given-names>A.</given-names> </name>  </person-group>   <article-title>Suspension arrays for high throughput, multiplexed single nucleotide polymorphism genotyping</article-title>               </element-citation> </ref>  <ref id="ref2"> <label>2</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Boonhama N., Kreuze J., Winter S., van der Vlugt R., Bergervoet J., Tomlinsona J., Mumforda R. Methods in virus diagnostics: From ELISA to next generation sequencing // Virus Research 186 (2014) 20–31.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Boonhama</surname> <given-names>N.</given-names> </name>  <name> <surname>Kreuze</surname> <given-names>J.</given-names> </name>  <name> <surname>Winter</surname> <given-names>S.</given-names> </name>  <name> <surname>Vlugt</surname> <given-names>R.</given-names> </name>  <name> <surname>Bergervoet</surname> <given-names>J.</given-names> </name>  <name> <surname>Tomlinsona</surname> <given-names>J.</given-names> </name>  <name> <surname>Mumforda</surname> <given-names>R.</given-names> </name>  </person-group>   <article-title>Methods in virus diagnostics: From ELISA to next generation sequencing</article-title>               </element-citation> </ref>  <ref id="ref3"> <label>3</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Cai H., White P.S., Torney D. Flow cytometry-based minisequencing: a new platform for high-throughput single-nucleotide polymorphism scoring. Genomics. 2000; 66: 135–143.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Cai</surname> <given-names>H.</given-names> </name>  <name> <surname>White</surname> <given-names>P. S.</given-names> </name>  <name> <surname>Torney</surname> <given-names>D.</given-names> </name>  </person-group>   <article-title>Flow cytometry-based minisequencing: a new platform for high-throughput single-nucleotide polymorphism scoring</article-title>               </element-citation> </ref>  <ref id="ref4"> <label>4</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Chao O.X., Bing Z., Xuan S.Z, Jun P.S., Fen W.S., Cong H.W. [et.al.] Evaluation of Microsphere-based xMAP Test for gyrA Mutation Identification in Mycobacterium Tuberculosis // Biomedical and Environmental Sciences, 2023, 36 (4): 384–387. doi: 10.3967/bes2023.046</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Chao</surname> <given-names>O. X.</given-names> </name>  <name> <surname>Bing</surname> <given-names>Z.</given-names> </name>  <name> <surname>Jun</surname> <given-names>P. S.</given-names> </name>  <name> <surname>Fen</surname> <given-names>W. S.</given-names> </name>  <name> <surname>Cong</surname> <given-names>H. W.</given-names> </name>  </person-group>   <article-title>Evaluation of Microsphere-based xMAP Test for gyrA Mutation Identification in Mycobacterium Tuberculosis</article-title>       <pub-id pub-id-type="doi">10.3967/bes2023.046</pub-id>        </element-citation> </ref>  <ref id="ref5"> <label>5</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Chen J., Iannone M.A., Li M.S. A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension. Genome Res. 2000; 10: 549–557.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Chen</surname> <given-names>J.</given-names> </name>  <name> <surname>Iannone</surname> <given-names>M. A.</given-names> </name>  <name> <surname>Li</surname> <given-names>M. S.</given-names> </name>  </person-group>   <article-title>A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension</article-title>               </element-citation> </ref>  <ref id="ref6"> <label>6</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Colinas R.J., Bellisario R., Pass K.A. Multiplexed genotyping of beta-globin variants from PCR-amplified newborn blood spot DNA by hybridization with allele-specific oligodeoxynucleotides coupled to an array of fluorescent microspheres. Clin Chem. 2000; 46: 996–998.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Colinas</surname> <given-names>R. J.</given-names> </name>  <name> <surname>Bellisario</surname> <given-names>R.</given-names> </name>  <name> <surname>Pass</surname> <given-names>K. A.</given-names> </name>  </person-group>   <article-title>Multiplexed genotyping of beta-globin variants from PCR-amplified newborn blood spot DNA by hybridization with allele-specific oligodeoxynucleotides coupled to an array of fluorescent microspheres</article-title>               </element-citation> </ref>  <ref id="ref7"> <label>7</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Cowan L.S., Diem L., Brake M.C., Crawford J.T. Transfer of a Mycobacterium tuberculosis genotyping method, spoligotyping, from a reverse line-blot hybridization, membrane-based assay to the Luminex multianalyte profiling system // Clin Microbiol. 2004; 42: 474–477.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Cowan</surname> <given-names>L. S.</given-names> </name>  <name> <surname>Diem</surname> <given-names>L.</given-names> </name>  <name> <surname>Brake</surname> <given-names>M. C.</given-names> </name>  <name> <surname>Crawford</surname> <given-names>J. T.</given-names> </name>  </person-group>   <article-title>Transfer of a Mycobacterium tuberculosis genotyping method, spoligotyping, from a reverse line-blot hybridization, membrane-based assay to the Luminex multianalyte profiling system</article-title> <source>Clin Microbiol</source> <year>2004</year>  <issue>42</issue>           </element-citation> </ref>  <ref id="ref8"> <label>8</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Diaz M.R., Fell J.W. High-throughput detection of pathogenic yeasts of the genus Trichosporon // Clin Microbiol. 2004; 42: 3696–3706.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Diaz</surname> <given-names>M. R.</given-names> </name>  <name> <surname>Fell</surname> <given-names>J. W.</given-names> </name>  </person-group>   <article-title>High-throughput detection of pathogenic yeasts of the genus Trichosporon</article-title> <source>Clin Microbiol</source> <year>2004</year>  <issue>42</issue>           </element-citation> </ref>  <ref id="ref9"> <label>9</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Dunbar S.A. Applications of Luminex® xMAP™ technology for rapid, high-throughput multiplexed nucleic acid detection // Clin Chim Acta., 2006, 363 (1): 71–82. DOI 10.1016/j.cccn.2005.06.023. EDN LNDLPB</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Dunbar</surname> <given-names>S. A.</given-names> </name>  </person-group>   <article-title>Applications of Luminex® xMAP™ technology for rapid, high-throughput multiplexed nucleic acid detection</article-title> <source>Clin Chim Acta</source> <year>2006</year>  <issue>363</issue>   <pub-id pub-id-type="doi">10.1016/j.cccn.2005.06.023</pub-id> <pub-id pub-id-type="custom" custom-type="edn">LNDLPB</pub-id>       </element-citation> </ref>  <ref id="ref10"> <label>10</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Dunbar S.A., Jacobson J.W. Application of the Luminex LabMAP in rapid screening for mutations in the cystic fibrosis transmembrane conductance regulator gene: a pilot study. Clin Chem. 2000; 46: 1498–1500.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Dunbar</surname> <given-names>S. A.</given-names> </name>  <name> <surname>Jacobson</surname> <given-names>J. W.</given-names> </name>  </person-group>   <article-title>Application of the Luminex LabMAP in rapid screening for mutations in the cystic fibrosis transmembrane conductance regulator gene: a pilot study</article-title>               </element-citation> </ref>  <ref id="ref11"> <label>11</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Dunbar S.A., Vander Zee C.A., Oliver K.G., Karem K.L., Jacobson J.W. Quantitative, multiplexed detection of bacterial pathogens: DNA and protein applications of the Luminex LabMAP™ system // Microbiol Methods. 2003; 53: 245–252.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Dunbar</surname> <given-names>S. A.</given-names> </name>  <name> <surname>Zee</surname> <given-names>C. A.</given-names> </name>  <name> <surname>Oliver</surname> <given-names>K. G.</given-names> </name>  <name> <surname>Karem</surname> <given-names>K. L.</given-names> </name>  <name> <surname>Jacobson</surname> <given-names>J. W.</given-names> </name>  </person-group>   <article-title>Quantitative, multiplexed detection of bacterial pathogens: DNA and protein applications of the Luminex LabMAP™ system</article-title> <source>Microbiol Methods</source> <year>2003</year>  <issue>53</issue>           </element-citation> </ref>  <ref id="ref12"> <label>12</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Fulton R.J., McDade R.L., Smith P.L., Kienker L.J., Kettman J.R., Jr. Advanced multiplexed analysis with the FlowMetrix™ system. Clin Chem. 1997; 43: 1749–1756.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Fulton</surname> <given-names>R. J.</given-names> </name>  <name> <surname>Smith</surname> <given-names>P. L.</given-names> </name>  <name> <surname>Kienker</surname> <given-names>L. J.</given-names> </name>  <name> <surname>Kettman</surname> <given-names>J. R.</given-names> </name>  </person-group>   <article-title>Advanced multiplexed analysis with the FlowMetrix™ system</article-title>               </element-citation> </ref>  <ref id="ref13"> <label>13</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Hadd A.G., Laosinchai-Wolf W., Novak C.R. Microsphere bead arrays and sequence validation of 5/7/9T genotypes for multiplex screening of cystic fibrosis polymorphisms. J Mol Diagn. 2004; 6: 348–355.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Hadd</surname> <given-names>A. G.</given-names> </name>  <name> <surname>Laosinchai-Wolf</surname> <given-names>W.</given-names> </name>  <name> <surname>Novak</surname> <given-names>C. R.</given-names> </name>  </person-group>   <article-title>Microsphere bead arrays and sequence validation of 5/7/9T genotypes for multiplex screening of cystic fibrosis polymorphisms</article-title>               </element-citation> </ref>  <ref id="ref14"> <label>14</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Iannone M.A., Taylor J.D., Chen J. Multiplexed single nucleotide polymorphism genotyping by oligonucleotide ligation and flow cytometry. Cytometry. 2000; 39: 131–140.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Iannone</surname> <given-names>M. A.</given-names> </name>  <name> <surname>Taylor</surname> <given-names>J. D.</given-names> </name>  <name> <surname>Chen</surname> <given-names>J.</given-names> </name>  </person-group>   <article-title>Multiplexed single nucleotide polymorphism genotyping by oligonucleotide ligation and flow cytometry</article-title>               </element-citation> </ref>  <ref id="ref15"> <label>15</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Iannone M.A., Taylor J.D., Chen J., Li M.S., Ye F., Weiner M.P. Microsphere-based single nucleotide polymorphism genotyping. Methods Mol Biol. 2003; 226: 123–134.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Iannone</surname> <given-names>M. A.</given-names> </name>  <name> <surname>Taylor</surname> <given-names>J. D.</given-names> </name>  <name> <surname>Chen</surname> <given-names>J.</given-names> </name>  <name> <surname>Li</surname> <given-names>M. S.</given-names> </name>  <name> <surname>Ye</surname> <given-names>F.</given-names> </name>  <name> <surname>Weiner</surname> <given-names>M. P.</given-names> </name>  </person-group>   <article-title>Microsphere-based single nucleotide polymorphism genotyping</article-title>               </element-citation> </ref>  <ref id="ref16"> <label>16</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Johnson S.C., Marshall D.J., Harms G. Multiplexed genetic analysis using an extended genetic alphabet. Clin Chem. 2004; 50: 2019–2027.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Johnson</surname> <given-names>S. C.</given-names> </name>  <name> <surname>Marshall</surname> <given-names>D. J.</given-names> </name>  <name> <surname>Harms</surname> <given-names>G.</given-names> </name>  </person-group>   <article-title>Multiplexed genetic analysis using an extended genetic alphabet</article-title>               </element-citation> </ref>  <ref id="ref17"> <label>17</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Lee S.-H., Walker D.R., Cregan P.B., Boerma H.R. Comparison of four flow cytometric SNP detection assays and their use in plant improvement. Theor Appl Genet. 2004 (Nov. 17).</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Walker</surname> <given-names>D. R.</given-names> </name>  <name> <surname>Cregan</surname> <given-names>P. B.</given-names> </name>  <name> <surname>Boerma</surname> <given-names>H. R.</given-names> </name>  </person-group>   <article-title>Comparison of four flow cytometric SNP detection assays and their use in plant improvement</article-title>               </element-citation> </ref>  <ref id="ref18"> <label>18</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Montagnana M., Lippi G. Cancer diagnostics: current concepts and future perspectives. Ann Transl Med. 2017; 5 (13): 268.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Montagnana</surname> <given-names>M.</given-names> </name>  <name> <surname>Lippi</surname> <given-names>G.</given-names> </name>  </person-group>   <article-title>Cancer diagnostics: current concepts and future perspectives</article-title>               </element-citation> </ref>  <ref id="ref19"> <label>19</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Musher D., Goldsmith E., Dunbar S. The association between hypercoagulable states or increased platelet adhesion/aggregation and bacterial colonization of intravenous catheters. J Infect Dis. 2002; 186: 769–773.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Musher</surname> <given-names>D.</given-names> </name>  <name> <surname>Goldsmith</surname> <given-names>E.</given-names> </name>  <name> <surname>Dunbar</surname> <given-names>S.</given-names> </name>  </person-group>   <article-title>The association between hypercoagulable states or increased platelet adhesion/aggregation and bacterial colonization of intravenous catheters</article-title>               </element-citation> </ref>  <ref id="ref20"> <label>20</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Paradis F.W., Simard R., Gaudet D. Quantitative assay for the detection of the V617F variant in the Janus kinase 2 (JAK2) gene using the Luminex xMAP technology // BMC Medical Genetics. 2010. V. 11, 54.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Paradis</surname> <given-names>F. W.</given-names> </name>  <name> <surname>Simard</surname> <given-names>R.</given-names> </name>  <name> <surname>Gaudet</surname> <given-names>D.</given-names> </name>  </person-group>   <article-title>Quantitative assay for the detection of the V617F variant in the Janus kinase 2 (JAK2) gene using the Luminex xMAP technology</article-title> <source>BMC Medical Genetics</source> <year>2010</year> <volume>11</volume>            </element-citation> </ref>  <ref id="ref21"> <label>21</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Peterson A.W., Wolf L.K., Georgiadis R.M. Hybridization of mismatched or partially matched DNA at surfaces // Am Chem Soc. 2002; 124:14601–14607.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Peterson</surname> <given-names>A. W.</given-names> </name>  <name> <surname>Wolf</surname> <given-names>L. K.</given-names> </name>  <name> <surname>Georgiadis</surname> <given-names>R. M.</given-names> </name>  </person-group>   <article-title>Hybridization of mismatched or partially matched DNA at surfaces</article-title> <source>Am Chem Soc</source> <year>2002</year>             </element-citation> </ref>  <ref id="ref22"> <label>22</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Pickering J.W., McMillin G.A., Gedge F., Hill H.R., Lyon E. Flow cytometric assay for genotyping Cytochrome P450 2C9 and 2C19: Comparison with a microelectronic DNA array. Am J Pharmacogenomics. 2004; 4: 199–207.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Pickering</surname> <given-names>J. W.</given-names> </name>  <name> <surname>Gedge</surname> <given-names>F.</given-names> </name>  <name> <surname>Hill</surname> <given-names>H. R.</given-names> </name>  <name> <surname>Lyon</surname> <given-names>E.</given-names> </name>  </person-group>   <article-title>Flow cytometric assay for genotyping Cytochrome P450 2C9 and 2C19: Comparison with a microelectronic DNA array</article-title>               </element-citation> </ref>  <ref id="ref23"> <label>23</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Pulumati A., Pulumati A., Dwarakanath B.S., Verma A., Papineni R.V.L. Technological advancements in cancer diagnostics: Improvements and limitations // Cancer Reports. 2023; 6: e1764. DOI 10.1002/cnr2.1764. EDN QXRNYI</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Pulumati</surname> <given-names>A.</given-names> </name>  <name> <surname>Dwarakanath</surname> <given-names>B. S.</given-names> </name>  <name> <surname>Verma</surname> <given-names>A.</given-names> </name>  </person-group>   <article-title>Technological advancements in cancer diagnostics: Improvements and limitations</article-title> <source>Cancer Reports</source> <year>2023</year>     <pub-id pub-id-type="doi">10.1002/cnr2.1764</pub-id> <pub-id pub-id-type="custom" custom-type="edn">QXRNYI</pub-id>       </element-citation> </ref>  <ref id="ref24"> <label>24</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Reslova N., Michna V., Kasny M., Mikel P., Kralik P. xMAP Technology: Applications in Detection of Pathogens // Front. Microbiol. 2017. V. 8. https://doi.org/10.3389/fmicb.2017.00055. EDN YXQOON</mixed-citation>    </citation-alternatives> <element-citation publication-type="web">  <person-group person-group-type="author">  <name> <surname>Reslova</surname> <given-names>N.</given-names> </name>  <name> <surname>Michna</surname> <given-names>V.</given-names> </name>  <name> <surname>Kasny</surname> <given-names>M.</given-names> </name>  <name> <surname>Mikel</surname> <given-names>P.</given-names> </name>  <name> <surname>Kralik</surname> <given-names>P.</given-names> </name>  </person-group>   <article-title> xMAP Technology: Applications in Detection of Pathogens</article-title> <source>Front. Microbiol.</source> <year>2017</year> <volume>8</volume>    <pub-id pub-id-type="doi">10.3389/fmicb.2017.00055</pub-id> <pub-id pub-id-type="custom" custom-type="edn">YXQOON</pub-id> <ext-link ext-link-type="uri">https://doi.org/10.3389/fmicb.2017.00055</ext-link>      </element-citation> </ref>  <ref id="ref25"> <label>25</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Spiro A., Lowe M. Quantitation of DNA sequences in environmental PCR products by a multiplexed, bead-based method. Appl Environ Microbiol. 2002; 68: 1010–1013.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Spiro</surname> <given-names>A.</given-names> </name>  <name> <surname>Lowe</surname> <given-names>M.</given-names> </name>  </person-group>   <article-title>Quantitation of DNA sequences in environmental PCR products by a multiplexed, bead-based method</article-title>               </element-citation> </ref>  <ref id="ref26"> <label>26</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Spiro A., Lowe M., Brown D. A bead-based method for multiplexed identification and quantitation of DNA sequences using flow cytometry. Appl Environ Microbiol. 2000; 66: 4258–4265.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Spiro</surname> <given-names>A.</given-names> </name>  <name> <surname>Lowe</surname> <given-names>M.</given-names> </name>  <name> <surname>Brown</surname> <given-names>D.</given-names> </name>  </person-group>   <article-title>A bead-based method for multiplexed identification and quantitation of DNA sequences using flow cytometry</article-title>               </element-citation> </ref>  <ref id="ref27"> <label>27</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Sung H., Ferlay J., Siegel R.L. [et al.] Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021; 71 (3): 209–249.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Sung</surname> <given-names>H.</given-names> </name>  <name> <surname>Ferlay</surname> <given-names>J.</given-names> </name>  <name> <surname>Siegel</surname> <given-names>R. L.</given-names> </name>  </person-group>   <article-title>Global cancer statisti: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries</article-title>               </element-citation> </ref>  <ref id="ref28"> <label>28</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Taniguchi H., Okamoto W., Muro K. [et al.] Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study // Neoplasia. 2018. V. 20. №12. P. 1219–1226.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Taniguchi</surname> <given-names>H.</given-names> </name>  <name> <surname>Okamoto</surname> <given-names>W.</given-names> </name>  <name> <surname>Muro</surname> <given-names>K.</given-names> </name>  </person-group>   <article-title>Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study</article-title> <source>Neoplasia</source> <year>2018</year> <volume>20</volume> <issue>12</issue> <fpage>1219</fpage> <lpage>1226</lpage>         </element-citation> </ref>  <ref id="ref29"> <label>29</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Taylor J.D., Briley D., Nguyen Q. Flow cytometric platform for high-throughput single nucleotide polymorphism analysis. BioTechniques. 2001; 30: 661–669.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Taylor</surname> <given-names>J. D.</given-names> </name>  <name> <surname>Briley</surname> <given-names>D.</given-names> </name>  <name> <surname>Nguyen</surname> <given-names>Q.</given-names> </name>  </person-group>   <article-title>Flow cytometric platform for high-throughput single nucleotide polymorphism analysis</article-title>               </element-citation> </ref>  <ref id="ref30"> <label>30</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Tempany C.M.C., Jayender J., Kapur T. [et al.] Multimodal imaging for improved diagnosis and treatment of cancers. Cancer. 2015; 121 (6): 817–827.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Jayender</surname> <given-names>J.</given-names> </name>  <name> <surname>Kapur</surname> <given-names>T.</given-names> </name>  </person-group>   <article-title>Multimodal imaging for improved diagnosis and treatment of cancers</article-title>               </element-citation> </ref>  <ref id="ref31"> <label>31</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Wallace J., Zhou Y., Usmani N. BARCODE-ALL: Accelerated and cost effective genetic risk-stratification in acute leukemia using spectrally addressable liquid bead microarrays. Leukemia. 2003; 17: 1404–1410.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Wallace</surname> <given-names>J.</given-names> </name>  <name> <surname>Zhou</surname> <given-names>Y.</given-names> </name>  <name> <surname>Usmani</surname> <given-names>N.</given-names> </name>  </person-group>   <article-title>BARCODE-ALL: Accelerated and cost effective genetic risk-stratification in acute leukemia using spectrally addressable liquid bead microarrays</article-title>               </element-citation> </ref>  <ref id="ref32"> <label>32</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Ye F., Li M.-S., Taylor J.D. Fluorescent microsphere-based readout technology for multiplexed human single nucleotide polymorphism analysis and bacterial identification. Hum Mutat. 2001; 17: 305–316.</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Ye</surname> <given-names>F.</given-names> </name>  <name> <surname>Taylor</surname> <given-names>J. D.</given-names> </name>  </person-group>   <article-title>Fluorescent microsphere-based readout technology for multiplexed human single nucleotide polymorphism analysis and bacterial identification</article-title>               </element-citation> </ref>  <ref id="ref33"> <label>33</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Yoshino T., Muro K., Yamaguchi K., Nishina T., Denda T., Kudo T., Okamoto W., Taniguchi H., Akagi K., Kajiwara T., Hironaka S., Satoh T. Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study // EBioMedicine. 2015. 2. 317–323. DOI 10.1016/j.ebiom.2015.02.007. EDN WRSSYP</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Yoshino</surname> <given-names>T.</given-names> </name>  <name> <surname>Muro</surname> <given-names>K.</given-names> </name>  <name> <surname>Yamaguchi</surname> <given-names>K.</given-names> </name>  <name> <surname>Nishina</surname> <given-names>T.</given-names> </name>  <name> <surname>Denda</surname> <given-names>T.</given-names> </name>  <name> <surname>Kudo</surname> <given-names>T.</given-names> </name>  <name> <surname>Okamoto</surname> <given-names>W.</given-names> </name>  <name> <surname>Taniguchi</surname> <given-names>H.</given-names> </name>  <name> <surname>Akagi</surname> <given-names>K.</given-names> </name>  <name> <surname>Kajiwara</surname> <given-names>T.</given-names> </name>  <name> <surname>Hironaka</surname> <given-names>S.</given-names> </name>  <name> <surname>Satoh</surname> <given-names>T.</given-names> </name>  </person-group>   <article-title>Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study</article-title> <source>EBioMedicine</source> <year>2015</year>     <pub-id pub-id-type="doi">10.1016/j.ebiom.2015.02.007</pub-id> <pub-id pub-id-type="custom" custom-type="edn">WRSSYP</pub-id>       </element-citation> </ref>  </ref-list> </back>  </book>