<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE book PUBLIC "-//NLM//DTD BITS Book Interchange DTD v2.3 20210610//EN" "BITS-book2.3.dtd"> <book xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" book-type="conference-proceedings" dtd-version="2.3" xml:lang="ru"> <front> <book-meta>  <book-id book-id-type="isbn">978-5-907965-64-5</book-id>   <book-id pub-id-type="doi">10.31483/a-10716</book-id>   <title-group>  <book-title xml:lang="ru">Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии</book-title>   <trans-title-group xml:lang="en"> <trans-title>Fundamental and applied research for key propriety areas of bioecology and biotechnology</trans-title> </trans-title-group>  </title-group>  <description xml:lang="ru"> <p>В сборнике представлены статьи участников VIII Всероссийской научно-практической конференции «Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии». В материалах сборника приведены результаты теоретических и прикладных изысканий представителей научного и образовательного сообщества в области биологии и медицины. Статьи представлены в авторской редакции.</p> </description>   <contrib-group>  <contrib contrib-type="editor" id="editor1">  <contrib-id contrib-id-type="role">chief_editor</contrib-id>    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> <email xlink:type="simple">antonov_67@mail.ru</email> </contrib>  <contrib contrib-type="editor" id="editor2">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ленгесова</surname> <given-names>Наталья Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Lengesova</surname> <given-names>Natal&#039;ia Anatol&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7512-6386</contrib-id> <email xlink:type="simple">lengesova@yandex.ru</email> </contrib>  <contrib contrib-type="editor" id="editor3">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Фирсова</surname> <given-names>Наталья Викторовна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Firsova</surname> <given-names>Natalia Viktorovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9907-8857</contrib-id> <email xlink:type="simple">n-firsova@mail.ru</email> </contrib>  </contrib-group>   <contrib-group>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm1">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm2">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm3">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Ленгесова</surname> <given-names>Наталья Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Lengesova</surname> <given-names>Natal&#039;ia Anatol&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7512-6386</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm4">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Беззубенкова</surname> <given-names>Ольга Евгеньевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Bezzubenkova</surname> <given-names>Ol&#039;ga Evgen&#039;evna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3243-6381</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm5">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Коняев</surname> <given-names>Игорь Сергеевич</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Koniaev</surname> <given-names>Igor&#039; Sergeevich</given-names> </name>  </name-alternatives>   </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm6">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Масленников</surname> <given-names>Андрей Викторович</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Maslennikov</surname> <given-names>Andrei Viktorovich</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1421-7484</contrib-id> </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm7">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Куницына</surname> <given-names>Анастасия Владимировна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Khambikova</surname> <given-names>Anastasiia Vladimirovna</given-names> </name>  </name-alternatives>   </contrib>  <contrib contrib-type="member-of-organizing-committee" id="orgcomm8">    <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Фирсова</surname> <given-names>Наталья Викторовна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Firsova</surname> <given-names>Natalia Viktorovna</given-names> </name>  </name-alternatives>  <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9907-8857</contrib-id> </contrib>  </contrib-group>   <event>  <event-desc xml:lang="ru">Фундаментальные и прикладные исследования по приоритетным направлениям биоэкологии и биотехнологии</event-desc>   <event-desc xml:lang="en">Fundamental and applied research for key propriety areas of bioecology and biotechnology</event-desc>   <conf-date> <day>22</day> <month>05</month> <year>2025</year> </conf-date>    <conf-loc xml:lang="ru">Ульяновск</conf-loc>  </event>   <publisher> <publisher-name>ИД «Среда»</publisher-name> </publisher>    <pub-date date-type="collection" publication-format="electronic" iso-8601-date="1900"> <year>1900</year> </pub-date>    <permissions>  <copyright-statement xml:lang="en">© 2025 Olesia V. Guzanova, Natalia V. Firsova, Elena V. Balatsiuk, Iuliia A. Anashkina, Elena I. Antonova</copyright-statement>   <copyright-statement xml:lang="ru">© 2025 Гузанова О. В., Фирсова Н. В., Балацюк Е. В., Анашкина Ю. А., Антонова Е. И.</copyright-statement>   <copyright-year>2025</copyright-year>  <copyright-holder xml:lang="ru">Гузанова О. В., Фирсова Н. В., Балацюк Е. В., Анашкина Ю. А., Антонова Е. И.</copyright-holder>   <copyright-holder xml:lang="en">Olesia V. Guzanova, Natalia V. Firsova, Elena V. Balatsiuk, Iuliia A. Anashkina, Elena I. Antonova</copyright-holder>    <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xml:lang="en" xlink:type="simple"> <license-p>This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0)</license-p> </license>   <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/" xml:lang="ru" xlink:type="simple"> <license-p>Это произведение доступно по лицензии Creative Commons Attribution 4.0 International (CC BY 4.0)</license-p> </license>   </permissions>  </book-meta> <book-part book-part-type="conference-paper"> <book-part-meta>  <book-id pub-id-type="doi">10.31483/r-138830</book-id>   <book-id custom-type="publisher-id" pub-id-type="custom">138830</book-id> <title-group>  <chapter-title xml:lang="ru">Сравнительные аспекты гистотопографии диспластического невуса и узловой меланомы (обзорная статья)</chapter-title>   <trans-title-group xml:lang="en"> <trans-title>Comparative aspects of histotopography of dysplastic nevus and nodular melanoma (review article)</trans-title> </trans-title-group>  </title-group>  <contrib-group>   <contrib contrib-type="author" id="author1">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Гузанова</surname> <given-names>Олеся Владимировна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Guzanova</surname> <given-names>Olesia Vladimirovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">kuznecovao979@gmail.com</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author2"> <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9907-8857</contrib-id>  <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Фирсова</surname> <given-names>Наталья Викторовна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Firsova</surname> <given-names>Natalia Viktorovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">n-firsova@mail.ru</email> <xref ref-type="aff" rid="aff2"/> </contrib>   <contrib contrib-type="author" id="author3">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Балацюк</surname> <given-names>Елена Валерьевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Balatsiuk</surname> <given-names>Elena Valer&#039;evna</given-names> </name>   </name-alternatives>   <xref ref-type="aff" rid="aff2"/> </contrib>   <contrib contrib-type="author" id="author4">   <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Анашкина</surname> <given-names>Юлия Анатольевна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Anashkina</surname> <given-names>Iuliia Anatol&#039;evna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">maela.loivissa@yandex.ru</email> <xref ref-type="aff" rid="aff1"/> </contrib>   <contrib contrib-type="author" id="author5"> <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3686-9686</contrib-id>  <name-alternatives>  <name name-style="eastern" xml:lang="ru"> <surname>Антонова</surname> <given-names>Елена Ивановна</given-names> </name>   <name name-style="western" xml:lang="en"> <surname>Antonova</surname> <given-names>Elena Ivanovna</given-names> </name>   </name-alternatives>  <email xlink:type="simple">antonov_67@mail.ru</email> <xref ref-type="aff" rid="aff2"/> </contrib>    <aff-alternatives id="aff1">   <aff xml:lang="ru">  <institution-wrap> <institution-id institution-id-type="ror">00j0x9b96</institution-id> <institution>Ульяновский государственный педагогический университет им. И.Н. Ульянова</institution> </institution-wrap>   <country>Россия</country> </aff>    <aff xml:lang="en">  <institution-wrap> <institution-id institution-id-type="ror">00j0x9b96</institution-id> <institution>Ulyanovsk State Pedagogical University named after I. N. Ulyanov</institution> </institution-wrap>   <country>Russia</country> </aff>     </aff-alternatives>  <aff-alternatives id="aff2">   <aff xml:lang="ru">  <institution>Научно-исследовательский центр фундаментальных и прикладных проблем биоэкологии и биотехнологии ФГБОУ ВО «Ульяновский государственный педагогический университет им. И.Н. Ульянова»</institution>   <country>Россия</country> </aff>    <aff xml:lang="en">  <institution>Nauchno-issledovatel&#039;skii tsentr fundamental&#039;nykh i prikladnykh problem bioekologii i biotekhnologii FGBOU VO &quot;Ul&#039;ianovskii gosudarstvennyi pedagogicheskii universitet im. I.N. Ul&#039;ianova&quot;</institution>   <country>Russia</country> </aff>   </aff-alternatives>  </contrib-group>   <fpage>72</fpage> <lpage>78</lpage>   <abstract xml:lang="ru"> <p>диспластические невусы (ДН) и узловая/нодулярная меланома (УМ) представляют собой пигментные новообразования кожи, которые могут быть сложными для дифференциальной диагностики. УМ – является наиболее агрессивным подтипом по сравнению с другими формами меланомы из-за отсутствия радиального роста. ДН чаще всего определяют, как промежуточное поражение между доброкачественными невусами и меланомой. ДН по клинической и гистологической картине схожи с меланомой. Данная статья направлена на выявление основных гистологических сходств и отличий ДН и УМ.</p> </abstract>           <kwd-group xml:lang="ru">  <kwd>BRAF</kwd>  <kwd>NRAS</kwd>  <kwd>меланоциты</kwd>  <kwd>невоидные клетки</kwd>  <kwd>диспластические невусы</kwd>  <kwd>узловая меланома</kwd>  </kwd-group>        </book-part-meta> </book-part> </front>  <back> <ref-list> <title>References</title>  <ref id="ref1"> <label>1</label> <citation-alternatives>  <mixed-citation xml:lang="ru">Ажикова А.К. Роль иммуногистохимического метода в исследованиях кожи / А.К. Ажикова // Актуальные исследования висцеральных систем в биологии и медицине: сборник материалов III Всероссийской научно-практической конференции с международным участием. – Астрахань, 2022. – C. 10–11. – DOI 10.54398/9785992614053_5. – EDN HMXFCN</mixed-citation>    </citation-alternatives> <element-citation publication-type="other">  <person-group person-group-type="author">  <name> <surname>Ажикова</surname> <given-names>А. 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