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Otsenka mutatsionnogo statusa genov BRAF, NRAS i CDKN2A v dobrokachestvennykh obrazovaniiakh kozhi
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- Published in:
- All-Russian scientific conference with International Participation «Fundamental and applied research for key propriety areas of bioecology and biotechnology»
- Authors:
- Anastasiia V. Khambikova 1 , Anastasiia K. Koroleva 1 , Atabeg B. Achilov 1 , Elena I. Antonova 1
- Work direction:
- Молекулярная биология, генетика, микробиология
- Pages:
- 66-73
- Received: 26 May 2023
- Rating:
- Article accesses:
- 798
- Published in:
- РИНЦ
1 Nauchno-issledovatel'skii tsentr fundamental'nykh i prikladnykh problem bioekologii i biotekhnologii FGBOU VO "Ul'ianovskii gosudarstvennyi pedagogicheskii universitet im. I.N. Ul'ianova"
- APA
For citation:
Khambikova A. V., Koroleva A. K., Achilov A. B., & Antonova E. I. (2023). Otsenka mutatsionnogo statusa genov BRAF, NRAS i CDKN2A v dobrokachestvennykh obrazovaniiakh kozhi. Fundamental and applied research for key propriety areas of bioecology and biotechnology, 66-73. Чебоксары: PH "Sreda". https://doi.org/10.31483/r-106992
- ВКонтакте
- РћРТвЂВВВВВВВВнокласснРСвЂВВВВВВВВРєРСвЂВВВВВВВВ
- РњРѕР№ Р В Р’В Р РЋРЎв„ўР В Р’В Р РЋРІР‚ВВВВВВВВРЎР‚
DOI: 10.31483/r-106992
Abstract
Невусы относят к доброкачественным меланоцитарным новообразованиям с неопределённым биологическим потенциалом. Между генами, ассоциированными с невусом и меланомой, а также между фенотипическими и клеточными особенностями невусов и меланомы проявляются выраженные корреляции. В связи с этим для эффективного мониторинга и ранней диагностики меланомы необходим одномоментный мультиплексный скрининг по всем основным драйверным мутациям. В статье отражены результаты молекулярно-генетических исследований мутаций генов BRAF, NRAS и CDKN2A пациентов с гистологическим заключением внутридермальный невус кожи.
References
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